WP2: Structural glycovaccinology

WP2 Structural glycovaccinology will foster the development of skills in studying carbohydrate-protein interactions with complementary techniques available at the two partners sites, including microarray strategies and NMR/SPR/ITC/ELISA. UL has applied glycoarray techniques to identify epitopes in glycans from Enterococcus faecium and E. faecalis as well as S. aureus, while GSK has used an integrated approach combing X- ray and NMR to elucidate the minimal epitope of Group B Streptococcus type III. The combination of techniques available to the ESRs will train them to analyze and tackle scientific problems from different angles.